Abstract : The papain-like protease (PLpro) of SARS-CoV2 is an attractive target for the development of novel drugs to combat COVID-19. However, discovering effective drug candidates often requires the production of recombinant PLpro with high purity and yield. Unfortunately, this process often involves automated chromatography systems that require expensive and sophisticated equipment. This study aimed to purify recombinant PLpro using a manual Ni-NTA chromatography system with a step elution approach. In Full article
Abstract : In present day almost all FPGA and ASIC in every application PLL are the part of the chip. With any variation in PLL frequency the complete performance of the design would be affected. At Deep Submicron technology nodes threshold voltage Vth shift will happen at different corners due to manufacturing process. When designer squeezes to achieve maximum performance and low voltage, the shift in Vth impacts the complete circuit/chip performance in addition to temperature variation. Present day appli Full article
Abstract : In The present work a circular inspired dodecagon shaped monopole patch antenna having a compact size of 30x22mm2 in MIMO configuration has been proposed. The proposed antenna is covering entire UWB band (2.-11 GHz) having a better isolations approx. -25 dB in the entire operating band, also it exhibits a better performance in terms of ECC and Diversity gain. The simulated and measured response are in a very close agreement to each other. Full article
Abstract : The purpose of this research is to examine the nutrient content of several sorghum varieties (Sorghum bicolor L. Moench.). filled in coconut manor regions in Manado City, North Sulawesi, Indonesia. This study employed an analysis of variance design with a completely random sample of sorghum varieties. The assortments that have been planted are Suri 3, Samurai 2, Kawali and Suri 4. Dry matter content, ash content, fat content, crude protein content, and crude fiber content were the variables that Full article
Abstract : This decision was made in order to choose between the got crops leguminosae Indigofera zollingeriana (Iz) and Brachiaria humicola (Bh), a tropical grass. The purpose of this consideration was to investigate the apparent magnitude of this received change in light of bearing limit and abandonment. The plan for this test was completely random, and for combination planted (C), it used a combination of four drugs from the planted area: C1, Iz, with dimensions of 1.0 m x 1.0 m and Bh, with dimensions Full article
Abstract : E-Commerce Web Applications testing has become a complex and tedious task because of their growing nature as well as increasing number of their probable customers. To ensure that these web applications are dependable, reliable testing tools as well as severe testing methods are required. In this paper various methods for web application evaluation have been discussed. The literature also addresses various tools used for performance testing of e-commerce web applications along with several parame Full article
Abstract : The paper discusses the policies and threats to natural wetlands resulted from urban and development activities, with a focus on Brullus Lake in Egypt. It highlights the geological, soil, and settlement characteristics of the area surrounding the lake, as well as the threats it faces including land drowning, loss of agricultural land, and uncontrolled expansion of fish farms. The paper also examines the urban environment and settlement characteristics of the area, including population density, r Full article
Abstract : This paper describes the process variation and it effect on ADC considering the all corners of the CMOS technology, explains how the process variation at every corner at deep submicron nodes and one of the electrical parameter of device components changes at device process corners. A brief working principle about Analog to digital circuits is given, as well as a explanation of process variations. This specific circuit design carried out using submicron foundry based process design kit. In a mode Full article
Abstract : In this research, natural fibers are used as composite materials as sound absorbers because they can reduce noise. Sound absorbers from natural fibers can reduce noise. It consists of a combination of coconut fiber and banana midrib as a filler and PVAC glue as a matrix. The variations of ratio of the coconut fiber and banana’s mid ribs are 1:1, 2:1, 1:2. To bind the material, PVAc glue was implemented, with its thickness ratio= 2 mm, 3 mm, and 4 mm. The sound-absorbing coefficient value refers Full article
Abstract : The transportation problem holds significant importance within the field of operations research, with a critical objective of minimizing transportation time to optimize fleet efficiency. This endeavor yields numerous benefits, including cost savings, enhanced customer service, increased competitiveness, a resilient supply chain network, and positive implications for sustainability and the environment. This research paper addresses the complex multi-dimensional transportation problem by focusing Full article
Abstract : This study was designed to perform a detailed structural, paleostress, and seismicity analysis of the Jordan Wadi Ibn Hammad dam site and evaluate the dam’s vulnerability. Lithologically, the dam's left abutment was constructed on the Upper Cretaceous rocks, comprised of limestones, silicified limestones, chalk, dolomite, tripoli, and chert. The structure setup of the dam site is controlled by the Dead Sea Transform Fault System (DST), the ENE-WSW segment of the dextral strike-slip Siwaqa Fault, Full article